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Anti-Slitrk1 Polyclonal Antibody

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货号 TMAB-12926

Anti-Slitrk1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Slitrk1。Anti-Slitrk1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Slitrk1 Polyclonal Antibody

Anti-Slitrk1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-12926

Anti-Slitrk1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Slitrk1。Anti-Slitrk1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍


生物活性
产品描述
Anti-Slitrk1 Polyclonal Antibody is a Rabbit antibody targeting Slitrk1. Anti-Slitrk1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Chicken,Dog,Pig,Cow,Horse,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Single-pass type I membrane protein (Potential).
组织特异性Expressed predominantly in the frontal lobe of the cerebral cortex of the brain. Also expressed in some astrocytic brain tumors such as astrocytomas, oligodendrogliomas, glioblastomas, gangliogliomas and primitive neuroectodermal tumors.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Slitrk1 is a member of a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the family. For example, Slitrk1 is expressed primarily in mature neurons. Overexpression of Slitrk1 in transfected neuronal cells induced unipolar neurites, while expression of the other Slitrk proteins inhibited neurite outgrowth, suggesting that these proteins are involved in the control of neurite outgrowth. While Slitrk1 variants have been suggested associated with Tourette’s Syndrome, it is thought to play only a minor role if at all.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Slitrk1
抗原种属
Human
基因名称
SLITRK1
基因ID
蛋白名称
SLIT and NTRK-like protein 1
Uniprot ID
功能
Enhances neuronal dendrite outgrowth.
化学信息
分子量Theoretical: 76 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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