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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-SLCO1C1 Polyclonal Antibody

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货号 TMAB-12918

Anti-SLCO1C1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SLCO1C1。Anti-SLCO1C1 Polyclonal Antibody 可用于 WB。

Anti-SLCO1C1 Polyclonal Antibody

Anti-SLCO1C1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-12918

Anti-SLCO1C1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SLCO1C1。Anti-SLCO1C1 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-SLCO1C1 Polyclonal Antibody is a Rabbit antibody targeting SLCO1C1. Anti-SLCO1C1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Multi-pass membrane protein. Note=Expressed in both luminal and abluminal membranes of brain capillary endothelial cells. Localized to the apical membrane and basal surfaces of choroid plexus
组织特异性Highly expressed in brain and in Leydig cells in testis. Detected in many brain regions with the exception of pons and cerebellum. Not strongly enriched in cerebral microvessels.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The organic anion transporter family of proteins mediate hepatic uptake of cardiac glycosides. OATP-F is a 712 amino acid member of the organic anion transporter protein family. As a multi-pass membrane protein, OATP-F mediates the Na+-independent, high affinity transport of the thyroid hormones thyroxine (T4) and rT3 and other organic anions. OATP-F is also thought to transport estrone-3-sulfate and sulfobromophthalein (BSP), triiodothyronine (T3) and 17-beta-glucuronosyl estradiol at a much lower efficiency. OATP-F is expressed highly in Leydig cells in testis and in brain.
抗原信息
免疫原
KLH conjugated synthetic peptide: human SLCO1C1/OATP-F
抗原种属
Human
基因名称
SLCO1C1
基因ID
53919
蛋白名称
Solute carrier organic anion transporter family member 1C1
Uniprot ID
Q9NYB5
功能
SLCO1C1 is a member of the organic anion transporter family. SLCO1C1 is a transmembrane receptor that mediates the sodium-independent uptake of thyroid hormones in brain tissues. This protein has particularly high affinity for the thyroid hormones thyroxine, tri-iodothyronine and reverse tri-iodothyronine. Polymorphisms in the gene encoding this protein may be associated with fatigue and depression in patients suffering from hyperthyroidism. Alternative splicing results in multiple transcript variants which produce 5 distinct proteins.
化学信息
分子量Theoretical: 79 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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