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Anti-SLC19A3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 SLC19A3。Anti-SLC19A3 Polyclonal Antibody 可用于 WB。
Anti-SLC19A3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 SLC19A3。Anti-SLC19A3 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,960 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
| 产品描述 | Anti-SLC19A3 Polyclonal Antibody is a Rabbit antibody targeting SLC19A3. Anti-SLC19A3 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Mouse (predicted:Human,Rat) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Plasma membrane. |
| 组织特异性 | Widely expressed but most abundant in placenta, kidney and liver. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| 浓度 | 1mg/ml |
| 研究背景 | This gene encodes a ubiquitously expressed transmembrane thiamine transporter that lacks folate transport activity. Mutations in this gene cause biotin-responsive basal ganglia disease (BBGD); a recessive disorder manifested in childhood that progresses to chronic encephalopathy, dystonia, quadriparesis, and death if untreated. Patients with BBGD have bilateral necrosis in the head of the caudate nucleus and in the putamen. Administration of high doses of biotin in the early progression of the disorder eliminates pathological symptoms while delayed treatment results in residual paraparesis, mild mental retardation, or dystonia. Administration of thiamine is ineffective in the treatment of this disorder. Experiments have failed to show that this protein can transport biotin. Mutations in this gene also cause a Wernicke's-like encephalopathy.[provided by RefSeq, Jan 2010] |
| 免疫原 | KLH conjugated synthetic peptide: human SLC19A3 |
| 抗原种属 | Human |
| 基因名称 | SLC19A3 |
| 基因ID | |
| 蛋白名称 | Thiamine transporter 2 |
| Uniprot ID | |
| 功能 | Mediates high affinity thiamine uptake, propably via a proton anti-port mechanism. Has no folate transport activity. |
| 分子量 | Theoretical: 56 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |