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Anti-SKOR2 Polyclonal Antibody

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货号 TMAB-12826

Anti-SKOR2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 SKOR2。Anti-SKOR2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-SKOR2 Polyclonal Antibody

Anti-SKOR2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-12826

Anti-SKOR2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 SKOR2。Anti-SKOR2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-SKOR2 Polyclonal Antibody is a Rabbit antibody targeting SKOR2. Anti-SKOR2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Dog,Cow,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cytoplasm.
组织特异性Expressed in cerebellum, spinal cord and testis. Isoform 2 is present in cerebellum (at protein level).
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The sloan kettering virus (Ski) family of nuclear oncoproteins act as transcriptional regulators of TGF-β by interacting directly with SMAD proteins. Fussel-18 (functional Smad-suppressing element on chromosome 18), also known as SKOR2 (Ski family transcriptional corepressor 2), LBX1 corepressor 1-like protein, ladybird homeobox corepressor 1-like protein or CORL2, is a 1,001 amino acid protein that belongs to the Ski family. Localizing to nucleus as well as cytoplasm, Fussel-18 is expressed in cerebellum, spinal cord and testis. Fussel-18 acts as an antagonist to TGF-β in the nervous system, possibly by functioning as a transcriptional repressor of SMAD2 and SMAD3. Existing as two alternatively spliced isoforms, the gene encoding Fussel-18 maps to human chromosome 18q21.1 and mouse chromosome 18 E3.
抗原信息
免疫原
KLH conjugated synthetic peptide: human SKOR2
抗原种属
Human
基因名称
SKOR2
基因ID
蛋白名称
SKI family transcriptional corepressor 2
Uniprot ID
功能
Exhibits transcriptional repressor activity (By similarity). Acts as a TGF-beta antagonist in the nervous system.
化学信息
分子量Theoretical: 104 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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