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Anti-Site 2 protease Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Site 2 protease。Anti-Site 2 protease Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。
Anti-Site 2 protease Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Site 2 protease。Anti-Site 2 protease Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
| 产品描述 | Anti-Site 2 protease Polyclonal Antibody is a Rabbit antibody targeting Site 2 protease. Anti-Site 2 protease Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 反应种属 | Mouse,Rat (predicted:Human,Cow,Horse,Sheep) |
| 应用 | WBIHC-PIHC-FrIF |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Membrane. Cytoplasm. |
| 组织特异性 | Expressed in heart, brain, placenta, lung, liver, muscle, kidney and pancreas. |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome); IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.[provided by RefSeq, Aug 2009] |
| 免疫原 | KLH conjugated synthetic peptide: human Site 2 protease |
| 抗原种属 | Human |
| 基因名称 | MBTPS2 |
| 基因ID | |
| 蛋白名称 | Membrane-bound transcription factor site-2 protease |
| Uniprot ID | |
| 功能 | Intramembrane proteolysis of sterol-regulatory element-binding proteins (SREBPs) within the first transmembrane segment thereby releasing the N-terminal segment with a portion of the transmembrane segment attached. Site-2 cleavage comes after site-1 cleavage which takes place in the lumenal loop. |
| 分子量 | Theoretical: 57 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |