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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-SIGLEC8 Polyclonal Antibody 2

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货号 TMAB-12795

Anti-SIGLEC8 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 SIGLEC8。Anti-SIGLEC8 Polyclonal Antibody 2 可用于 WB。

Anti-SIGLEC8 Polyclonal Antibody 2

Anti-SIGLEC8 Polyclonal Antibody 2

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Rating icon 还可以
货号 TMAB-12795

Anti-SIGLEC8 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 SIGLEC8。Anti-SIGLEC8 Polyclonal Antibody 2 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-SIGLEC8 Polyclonal Antibody 2 is a Rabbit antibody targeting SIGLEC8. Anti-SIGLEC8 Polyclonal Antibody 2 can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Single-pass type I membrane protein.
组织特异性Expressed specifically on eosinophils.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM; MIM 603492) that mediates an association with SLAM-associated protein (SAP; MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]).[supplied by OMIM, May 2010]
抗原信息
免疫原
KLH conjugated synthetic peptide: human SIGLEC8
抗原种属
Human
基因名称
SIGLEC8
基因ID
27181
蛋白名称
Sialic acid-binding Ig-like lectin 8
Uniprot ID
Q9NYZ4
功能
Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3-linked sialic acid. Also binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
化学信息
分子量Theoretical: 50 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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