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Anti-SIGLEC11 Polyclonal Antibody

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货号 TMAB-12792

Anti-SIGLEC11 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 SIGLEC11。Anti-SIGLEC11 Polyclonal Antibody 可用于 WB。

Anti-SIGLEC11 Polyclonal Antibody

Anti-SIGLEC11 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-12792

Anti-SIGLEC11 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 SIGLEC11。Anti-SIGLEC11 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍


生物活性
产品描述
Anti-SIGLEC11 Polyclonal Antibody is a Rabbit antibody targeting SIGLEC11. Anti-SIGLEC11 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Single-pass type I membrane protein.
组织特异性Expressed by macrophages in various tissues including Kupffer cells. Also found in brain microglia.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. This family member mediates anti-inflammatory and immunosuppressive signaling. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
抗原信息
免疫原
KLH conjugated synthetic peptide: human SIGLEC11
抗原种属
Human
基因名称
SIGLEC11
基因ID
蛋白名称
Sialic acid-binding Ig-like lectin 11
Uniprot ID
功能
Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,8-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules.
化学信息
分子量Theoretical: 74 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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