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Anti-SIGLEC11 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 SIGLEC11。Anti-SIGLEC11 Polyclonal Antibody 可用于 WB。
Anti-SIGLEC11 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 SIGLEC11。Anti-SIGLEC11 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
| 产品描述 | Anti-SIGLEC11 Polyclonal Antibody is a Rabbit antibody targeting SIGLEC11. Anti-SIGLEC11 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Human |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 组织特异性 | Expressed by macrophages in various tissues including Kupffer cells. Also found in brain microglia. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. This family member mediates anti-inflammatory and immunosuppressive signaling. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] |
| 免疫原 | KLH conjugated synthetic peptide: human SIGLEC11 |
| 抗原种属 | Human |
| 基因名称 | SIGLEC11 |
| 基因ID | |
| 蛋白名称 | Sialic acid-binding Ig-like lectin 11 |
| Uniprot ID | |
| 功能 | Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,8-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. |
| 分子量 | Theoretical: 74 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |