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Anti-SHBG Polyclonal Antibody 2

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货号 TMAB-12761

Anti-SHBG Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 SHBG。Anti-SHBG Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF。

Anti-SHBG Polyclonal Antibody 2

Anti-SHBG Polyclonal Antibody 2

一键复制产品信息
Rating icon 还可以
货号 TMAB-12761

Anti-SHBG Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 SHBG。Anti-SHBG Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-SHBG Polyclonal Antibody 2 is a Rabbit antibody targeting SHBG. Anti-SHBG Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Dog,Cow,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted . Note=In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis.
组织特异性Isoform 1 and isoform 2 are present in liver and testis.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Sex hormone binding globulin (SHBG) is a glycoprotein synthesized by the liver. Circulating androgen and estrogen concentrations influence SHBG synthesis. Elevated testosterone, for example, causes SHBG synthesis to decrease, whereas high estrogen stimulates SHBG production. The regulation of SHBG synthesis, combined with SHBG's higher affinity for testosterone, impacts bioavailable testosterone levels. SHBG binds up to 98 percent of the steroid hormones in the blood including 5a-dihydrotestosterone (DHT), testosterone and androstenediol with particularly high affinity, and estradiol and estrone with slightly lower affinity.
抗原信息
免疫原
KLH conjugated synthetic peptide: human SHBG
抗原种属
Human
基因名称
SHBG
基因ID
蛋白名称
Sex hormone-binding globulin
Uniprot ID
功能
Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration.
化学信息
分子量Theoretical: 44 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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