购物车
全部删除
  • TargetMol
    您的购物车当前为空
前往下单页继续购物
顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-SGOL2 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-12738

Anti-SGOL2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SGOL2。Anti-SGOL2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-SGOL2 Polyclonal Antibody

Anti-SGOL2 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-12738

Anti-SGOL2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SGOL2。Anti-SGOL2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,785
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
大包装 & 定制
加入购物车
TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
查看更多
资源下载:
产品操作手册

产品介绍

生物活性
产品描述
Anti-SGOL2 Polyclonal Antibody is a Rabbit antibody targeting SGOL2. Anti-SGOL2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Chromosome > centromere. Chromosome > centromere > kinetochore. During meiosis I, accumulates at centromeres during diplotene, and co-localizes differentially with the cohesin subunits RAD21 and REC8 at metaphase I centromeres. SGO2 and RAD21 change their relative distributions during telophase I when sister-kinetochore association is lost. During meiosis II, it shows a striking tension-dependent redistribution within centromeres throughout chromosome congression during prometaphase II, as it does during mitosis (By similarity). In Hela cells, localizes at centromeres throughout prophase until metaphase and disappears at anaphase. Centromeric localization requires the presence of BUB1 and AUKRB.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景SGO2 (Shugoshin 2) is a Protein Coding gene. Diseases associated with SGO2 include Perrault Syndrome. Among its related pathways are Mitotic Metaphase and Anaphase and Signaling by GPCR.
抗原信息
免疫原
KLH conjugated synthetic peptide: mouse SGOL2
抗原种属
Mouse
基因名称
SGO2
基因ID
151246
蛋白名称
Shugoshin 2
功能
Cooperates with PPP2CA to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Has a crucial role in protecting REC8 at centromeres from cleavage by separase. During meiosis, protects centromeric cohesion complexes until metaphase II/anaphase II transition, preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate gametogenesis. May act by targeting PPP2CA to centromeres, thus leading to cohesin dephosphorylation (By similarity). Essential for recruiting KIF2C to the inner centromere and for correcting defective kinetochore attachments.
化学信息
分子量Theoretical: 145 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

  • 稀释 计算器
Related Tags: buy Anti-SGOL2 Polyclonal Antibody | purchase Anti-SGOL2 Polyclonal Antibody | Anti-SGOL2 Polyclonal Antibody cost | order Anti-SGOL2 Polyclonal Antibody | Anti-SGOL2 Polyclonal Antibody molecular weight