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顶部产品介绍偶联与修饰抗原信息化学信息储存和溶解信息计算器

Anti-SETD7 Monoclonal Antibody (7S223)

Synonyms: SET9, SET7/9, SET7, KMT7
货号 TMAT-1442 一键复制产品信息
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Anti-SETD7 Monoclonal Antibody (7S223) 是一种 Mouse 抗体，靶向 SETD7。Anti-SETD7 Monoclonal Antibody (7S223) 可用于 WB,FCM。

Anti-SETD7 Monoclonal Antibody (7S223)

一键复制产品信息
Rating icon 还可以
货号 TMAT-1442

别名 SET9, SET7/9, SET7, KMT7

Anti-SETD7 Monoclonal Antibody (7S223) 是一种 Mouse 抗体，靶向 SETD7。Anti-SETD7 Monoclonal Antibody (7S223) 可用于 WB,FCM。

Anti-SETD7 Monoclonal Antibody (7S223)
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产品介绍

生物活性
产品描述
Anti-SETD7 Monoclonal Antibody (7S223) is a Mouse antibody targeting SETD7. Anti-SETD7 Monoclonal Antibody (7S223) can be used in WB,FCM.
别名
SET9, SET7/9, SET7, KMT7
Ig Type
IgG2a
克隆号
7S223
反应种属
Human,Rat,Monkey
应用WBFCM
推荐剂量
WB: 1/500-1/2000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/mL
研究背景Histone methyltransferase that specifically monomethylates Lys-4 of histone H3. H3 Lys-4 methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates Lys-189 of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates Lys-372 of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human SETD7 (AA: 107-366) expressed in E. Coli.
抗原种属
Human
基因名称
SETD7
基因ID
80854
蛋白名称
Histone-lysine N-methyltransferase SETD7
Uniprot ID
Q8WTS6
化学信息
分子量Theoretical: 40.7 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器
  • 配液 计算器
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