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Anti-SerpinB2 Polyclonal Antibody

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货号 TMAB-12684

Anti-SerpinB2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SerpinB2。Anti-SerpinB2 Polyclonal Antibody 可用于 FCM。

Anti-SerpinB2 Polyclonal Antibody

Anti-SerpinB2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-12684

Anti-SerpinB2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SerpinB2。Anti-SerpinB2 Polyclonal Antibody 可用于 FCM。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-SerpinB2 Polyclonal Antibody is a Rabbit antibody targeting SerpinB2. Anti-SerpinB2 Polyclonal Antibody can be used in FCM.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Pig,Cow,Rabbit)
应用FCM
推荐剂量
FCM: 2μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Secreted, extracellular space.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景SerpinB2 is a serine proteinase inhibitor of the ovalbumin like B clade of serpins. It was first discovered in the placenta, and given the name PAI-2 because of the ability to inhibit urokinase plasminogen activator (u-PA) at low micromolar efficiency. SerpinB2 also inhibits tissue plasminogen activator (t-PA), but with micromolar efficiency, and PAI-1 is much more efficient that SerpinB2 on both forms of plasminogen activator. The structure of PAI-2 is not terribly similar to PAI-1, however, which is an E clade serpin. SerpinB2 is made by many cell types, and is found intracellularly as an unglycosylated kDa protein, and secreted as a 60 kDa protein. SerpinB2 is found in saliva, secreted by gingival fibroblasts, and in the skin. SerpinB2 levels are elevated in serum during pregnancy, and in leukemia, breast cancer and ovarian cancer, although it was lowered in some cancers.A shorter SerpinB2 isoform of 382 amino acids, has been reported, with a predicted mass of 43.1 kDa and a pI of 5.69. The shorter form has a deletion just after the start of the mature protein, but it is unclear what the relative production and distribution is for the shorter sequence.
抗原信息
免疫原
KLH conjugated synthetic peptide: human PAI-2
抗原种属
Human
基因名称
SERPINB2
基因ID
5055
蛋白名称
Plasminogen activator inhibitor 2
Uniprot ID
P05120
功能
Inhibits urokinase-type plasminogen activator.
化学信息
分子量Theoretical: 47 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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