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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-SERPINA12 Polyclonal Antibody

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货号 TMAB-12681

Anti-SERPINA12 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SERPINA12。Anti-SERPINA12 Polyclonal Antibody 可用于 WB,ELISA。

Anti-SERPINA12 Polyclonal Antibody

Anti-SERPINA12 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-12681

Anti-SERPINA12 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SERPINA12。Anti-SERPINA12 Polyclonal Antibody 可用于 WB,ELISA。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
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产品介绍

生物活性
产品描述
Anti-SERPINA12 Polyclonal Antibody is a Rabbit antibody targeting SERPINA12. Anti-SERPINA12 Polyclonal Antibody can be used in WB,ELISA.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat)
应用WBELISA
推荐剂量
WB: 1:500-2000; ELISA: 1:5000-10000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted.
组织特异性Expressed in visceral adipose tissues.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景May modulates insulin action conceivably only in the presence of its yet undefined target proteases in white adipose tissues. Serpins are the largest and most diverse family of protease inhibitors. Most serpins control proteolytic cascades, certain serpins do not inhibit enzymes, but instead perform diverse functions such as storage (ovalbumin, in egg white), hormone carriage proteins (thyroxine-binding globulin, cortisol-binding globulin) and tumor suppressor genes (maspin). Most inhibitory serpins target chymotrypsin-like serine proteases. These enzymes are defined by the presence of a nucleophilic serine residue in their catalytic site. Some serpins inhibit other classes of protease. A number of such serpins have been shown to target cysteine proteases. These enzymes differ from serine proteases in that they are defined by the presence of a nucleophilic cysteine residue, rather than a serine residue, in their catalytic site. SerpinA12, also known as OL-64, Visceral adipose tissue-derived serine protease inhibitor, Vaspin, Visceral adipose-specific serpin and SERPINA12, is a secreted protein which belongs to the serpin family. SerpinA12 / Vaspin is expressed in visceral adipose tissues. It may modulates insulin action conceivably only in the presence of its yet undefined target proteases in white adipose tissues. SerpinA12 / Vaspin may be the compensatory molecule in the pathogenesis of metabolic syndrome and SerpinA12 / Vaspin recombinant protein or vaspin-mimicking agents such as vaspin analogs, antibodies or small molecule agents may be the link to drug discovery and development.
抗原信息
免疫原
KLH conjugated synthetic peptide: human SERPINA12/Vaspin
抗原种属
Human
基因名称
SERPINA12
基因ID
145264
蛋白名称
Serpin A12
Uniprot ID
Q8IW75
功能
May modulates insulin action conceivably only in the presence of its yet undefined target proteases in white adipose tissues.
化学信息
分子量Theoretical: 45 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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