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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Securin Polyclonal Antibody

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货号 TMAB-12632

Anti-Securin Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Securin。Anti-Securin Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-Securin Polyclonal Antibody

Anti-Securin Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-12632

Anti-Securin Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Securin。Anti-Securin Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-Securin Polyclonal Antibody is a Rabbit antibody targeting Securin. Anti-Securin Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Pig,Horse)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The encoded protein is a homolog of yeast securing proteins, which prevent separins from promoting sister chromatid separation. It is an anaphase-promoting complex (APC) substrate that associates with a separin until activation of the APC. The gene product has transforming activity in vitro and tumorigenic activity in vivo, and the gene is highly expressed in various tumors. The gene product contains 2 PXXP motifs, which are required for its transforming and tumorigenic activities, as well as for its stimulation of basic fibroblast growth factor expression. It also contains a destruction box (D box) that is required for its degradation by the APC. The acidic C-terminal region of the encoded protein can act as a transactivation domain. The gene product is mainly a cytosolic protein, although it partially localizes in the nucleus. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2013].
抗原信息
免疫原
KLH conjugated synthetic peptide: human PTTG1
抗原种属
Human
基因名称
PTTG1
基因ID
9232
蛋白名称
Securin
Uniprot ID
O95997
功能
Expressed at low level in most tissues, except in adult testis, where it is highly expressed. Overexpressed in many patients suffering from pituitary adenomas, primary epithelial neoplasias, and esophageal cancer.
化学信息
分子量Theoretical: 22-28 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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