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Anti-SCNN1B Polyclonal Antibody 是一种 Rabbit 抗体,靶向 SCNN1B。Anti-SCNN1B Polyclonal Antibody 可用于 WB,ICC/IF。
Anti-SCNN1B Polyclonal Antibody 是一种 Rabbit 抗体,靶向 SCNN1B。Anti-SCNN1B Polyclonal Antibody 可用于 WB,ICC/IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,795 | 5日内发货 |
| 产品描述 | Anti-SCNN1B Polyclonal Antibody is a Rabbit antibody targeting SCNN1B. Anti-SCNN1B Polyclonal Antibody can be used in WB,ICC/IF. |
| Ig Type | IgG |
| 反应种属 | Human (predicted:Mouse,Rat,Pig,Horse,Rabbit) |
| 应用 | WBICC/IF |
| 推荐剂量 | WB: 1:500-2000; ICC/IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Apical cell membrane; Multi-pass membrane protein. Note=Apical membrane of epithelial cells. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | SCNN1B is a subunit of the epithelial sodium channel, ENaC. ENac has high sodium selectivity, low conductance, and amiloride sensitivity. The functional channel of ENaC is composed of at least 3 subunits, alpha (SCNN1A), beta (SCNN1B), and gamma (SCNN1G). The 3 subunits show sequence similarities to one another, indicating descent from a common ancestral gene. Each encodes a protein containing 2 transmembrane domains, with intracellular amino and carboxyl termini. |
| 免疫原 | KLH conjugated synthetic peptide: human SCNN1B |
| 抗原种属 | Human |
| 基因名称 | SCNN1B |
| 基因ID | |
| 蛋白名称 | Epithelial sodium channel subunit beta |
| Uniprot ID | |
| 功能 | Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception. |
| 分子量 | Theoretical: 73 kDa. Actual: 95-100/65-75 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |