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Anti-SCN11A Polyclonal Antibody

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货号 TMAB-12584

Anti-SCN11A Polyclonal Antibody 是一种 Rabbit 抗体,靶向 SCN11A。Anti-SCN11A Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-SCN11A Polyclonal Antibody

Anti-SCN11A Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-12584

Anti-SCN11A Polyclonal Antibody 是一种 Rabbit 抗体,靶向 SCN11A。Anti-SCN11A Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍


生物活性
产品描述
Anti-SCN11A Polyclonal Antibody is a Rabbit antibody targeting SCN11A. Anti-SCN11A Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Chicken,Dog,Pig,Cow,Horse,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Multi-pass membrane protein.
组织特异性Expressed in the dorsal root ganglia and trigeminal ganglia, olfactory bulb, hippocampus, cerebellar cortex, spinal cord, spleen, small intestine and placenta.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Voltage gated sodium channels are membrane protein complexes that play a fundamental role in generating and transmitting action potentials in neuronal cells. SCN11A (Sodium channel, voltage gated, type XI, alpha subunit) mediates the voltage dependent sodium ion permeability and conductance. It forms the pore of the sodium selective channel through which sodium ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin resistant sodium channel isoform.
抗原信息
免疫原
KLH conjugated synthetic peptide: human SCN11A/NAV1.9
抗原种属
Human
基因名称
SCN11A
基因ID
蛋白名称
Sodium channel protein type 11 subunit alpha
Uniprot ID
功能
This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant sodium channel isoform. Also involved, with the contribution of the receptor tyrosine kinase NTRK2, in rapid BDNF-evoked neuronal depolarization.
化学信息
分子量Theoretical: 197 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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