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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-SAFB Polyclonal Antibody

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货号 TMAB-12475

Anti-SAFB Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SAFB。Anti-SAFB Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-SAFB Polyclonal Antibody

Anti-SAFB Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-12475

Anti-SAFB Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SAFB。Anti-SAFB Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-SAFB Polyclonal Antibody is a Rabbit antibody targeting SAFB. Anti-SAFB Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Pig,Cow,Horse,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus.
组织特异性Expressed at high levels in the CNS and at low levels in the liver. Expressed in a wide number of breast cancer cell lines.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Heterogeneous nuclear ribonucleoproteins (hnRNPs) constitute a set of polypeptides that contribute to pre-mRNA processing and transport. hnRNPs also bind heterogeneous nuclear RNA (hnRNA), the transcripts produced by RNA polymerase II. SAF-B (scaffold attachment factor B) is a nuclear matrix-associated protein that binds to matrix- or scaffold-associating regions (MARs or SARs) on DNA and interacts with RNA polymerase II and serine-/arginine-rich RNA processing factors (SR proteins). SAF-B, also designated HAP (hnRNP A1 associated protein) and HET (HSP 27-ERE-TATA-binding protein) is a proven hnRNP protein that has a speckled distribution in the nucleus and, in response to stress agents such as heat shock, is recruited to a few, large nuclear granules, called perichromatin granules. SAF-B also binds to the estrogen receptor (ER) and is expressed in several breast cancer cell lines at varying levels. Subsequently, SAF-B may play a role in breast cancer by mediating cellular proliferation and division.
抗原信息
免疫原
KLH conjugated synthetic peptide: human SAFB
抗原种属
Human
基因名称
SAFB2
基因ID
9667
蛋白名称
Scaffold attachment factor B2
Uniprot ID
Q14151
功能
Binds to scaffold/matrix attachment region (S/MAR) DNA. Can function as an estrogen receptor corepressor and can also inhibit cell proliferation.
化学信息
分子量Theoretical: 107 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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