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Anti-SAE2/UBA2 Polyclonal Antibody

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货号 TMAB-12473

Anti-SAE2/UBA2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 SAE2/UBA2。Anti-SAE2/UBA2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-SAE2/UBA2 Polyclonal Antibody

Anti-SAE2/UBA2 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-12473

Anti-SAE2/UBA2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 SAE2/UBA2。Anti-SAE2/UBA2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-SAE2/UBA2 Polyclonal Antibody is a Rabbit antibody targeting SAE2/UBA2. Anti-SAE2/UBA2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Dog,Horse,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 (MIM 613294) and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010]
抗原信息
免疫原
KLH conjugated synthetic peptide: human SAE2
抗原种属
Human
基因名称
UBA2
基因ID
蛋白名称
SUMO-activating enzyme subunit 2
Uniprot ID
功能
The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.
化学信息
分子量Theoretical: 71 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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