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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-RUNX1T1 Polyclonal Antibody

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货号 TMAB-12427

Anti-RUNX1T1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 RUNX1T1。Anti-RUNX1T1 Polyclonal Antibody 可用于 WB。

Anti-RUNX1T1 Polyclonal Antibody

Anti-RUNX1T1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-12427

Anti-RUNX1T1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 RUNX1T1。Anti-RUNX1T1 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-RUNX1T1 Polyclonal Antibody is a Rabbit antibody targeting RUNX1T1. Anti-RUNX1T1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Chicken,Dog,Pig,Horse,Rabbit)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Most abundantly expressed in brain. Lower levels in lung, heart, testis and ovary.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景RUNX1T1 is a putative zinc finger transcription factor and oncoprotein. In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Several transcript variants encoding multiple isoforms have been found for this gene.
抗原信息
免疫原
KLH conjugated synthetic peptide: human RUNX1T1/ETO
抗原种属
Human
基因名称
RUNX1T1
基因ID
862
蛋白名称
Protein CBFA2T1
Uniprot ID
Q06455
功能
Homotetramer. Heterotetramer with CBFA2T2 and CBFA2T3. Interacts with TCF12, SIN3A, HDAC1, HDAC2, HDAC3, NCOR1 and NCOR2. Interacts with ATN1 (via its N-terminus); the interaction enhances the transcriptional repression.
化学信息
分子量Theoretical: 66 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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