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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-RRAS Polyclonal Antibody

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货号 TMAB-12389

Anti-RRAS Polyclonal Antibody 是一种 Rabbit 抗体，靶向 RRAS。Anti-RRAS Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-RRAS Polyclonal Antibody

Anti-RRAS Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-12389

Anti-RRAS Polyclonal Antibody 是一种 Rabbit 抗体，靶向 RRAS。Anti-RRAS Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-RRAS Polyclonal Antibody is a Rabbit antibody targeting RRAS. Anti-RRAS Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Pig,Cow,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Lipid-anchor; Cytoplasmic side (By similarity). Note=Inner surface of plasma membrane possibly with attachment requiring acylation of the C-terminal cysteine (By similarity with RAS).
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景H-Ras, K-Ras and N-Ras represent the prototype members of a family of small G proteins that are frequently activated to an oncogenic state in a wide variety of human tumors. Activation is due to point mutations at either position 12 or 61 within their coding sequence. Such mutations cause these proteins to be constitutively converted to their active, rather than the inactive, GDP-bound state. The related human R-Ras gene was initially cloned by low stringency hybridization methods. The R-Ras protein has been shown to interact with the Bcl-2 gene product involved in a signaling pathway that intervenes with apoptosis. Positions 38 and 87 (analogous to positions 12 and 61 in H-Ras) mutants of R-Ras have been shown to be capable of activating oncogenic function. Data has been obtained indicating that R-Ras may exert its biological effect by means of modulating the activity of the Raf-1 kinase on its direct downstream effectors.
抗原信息
免疫原
KLH conjugated synthetic peptide: human RRAS
抗原种属
Human
基因名称
RRAS
基因ID
6237
蛋白名称
Ras-related protein R-Ras
Uniprot ID
P10301
功能
Regulates the organization of the actin cytoskeleton.
化学信息
分子量Theoretical: 23 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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