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Anti-RRAGA+RRAGB Polyclonal Antibody

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货号 TMAB-12387

Anti-RRAGA+RRAGB Polyclonal Antibody 是一种 Rabbit 抗体，靶向 RRAGA+RRAGB。Anti-RRAGA+RRAGB Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-RRAGA+RRAGB Polyclonal Antibody

Anti-RRAGA+RRAGB Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-12387

Anti-RRAGA+RRAGB Polyclonal Antibody 是一种 Rabbit 抗体，靶向 RRAGA+RRAGB。Anti-RRAGA+RRAGB Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-RRAGA+RRAGB Polyclonal Antibody is a Rabbit antibody targeting RRAGA+RRAGB. Anti-RRAGA+RRAGB Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Dog,Pig,Horse,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus. Lysosome. Note=Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state. Colocalizes in vivo with adenovirus E3-14.7K mainly to the cytoplasm especially near the nuclear membrane and in discrete foci on or near the plasma membrane.
组织特异性Ubiquitously expressed with highest levels of expression in skeletal muscle, heart, and brain.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Involved in the RCC1/Ran-GTPase pathway. RRAGA may play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity. biquitously expressed with highest levels of expression in skeletal muscle, heart, and brain.
抗原信息
免疫原
KLH conjugated synthetic peptide: human RRAGA and RRAGB
抗原种属
Human
基因名称
Rraga
基因ID
10670
蛋白名称
Ras-related GTP-binding protein A
Uniprot ID
Q7L523
功能
Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity. Required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death.
化学信息
分子量Theoretical: 37 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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