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顶部产品介绍偶联与修饰抗原信息化学信息储存和溶解信息计算器

Anti-RPA1 Monoclonal Antibody (5L459)

Synonyms: RPA70, RP-A, RF-A, REPA1, PFBMFT6, MST075, HSSB
货号 TMAT-0955 一键复制产品信息
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Anti-RPA1 Monoclonal Antibody (5L459) 是一种 Mouse 抗体，靶向 RPA1。Anti-RPA1 Monoclonal Antibody (5L459) 可用于 WB,IHC,IF,FCM。

Anti-RPA1 Monoclonal Antibody (5L459)

一键复制产品信息
Rating icon 还可以
货号 TMAT-0955

别名 RPA70, RP-A, RF-A, REPA1, PFBMFT6, MST075, HSSB

Anti-RPA1 Monoclonal Antibody (5L459) 是一种 Mouse 抗体，靶向 RPA1。Anti-RPA1 Monoclonal Antibody (5L459) 可用于 WB,IHC,IF,FCM。

Anti-RPA1 Monoclonal Antibody (5L459)
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产品介绍

生物活性
产品描述
Anti-RPA1 Monoclonal Antibody (5L459) is a Mouse antibody targeting RPA1. Anti-RPA1 Monoclonal Antibody (5L459) can be used in WB,IHC,IF,FCM.
别名
RPA70, RP-A, RF-A, REPA1, PFBMFT6, MST075, HSSB
Ig Type
IgG1
克隆号
5L459
反应种属
Human,Monkey
应用WBIHCIFFCM
推荐剂量
WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/mL
研究背景This gene encodes the largest subunit of the heterotrimeric Replication Protein A (RPA) complex, which binds to single-stranded DNA (ssDNA), forming a nucleoprotein complex that plays an important role in DNA metabolism, being involved in DNA replication, repair, recombination, telomere maintenance, and co-ordinating the cellular response to DNA damage through activation of the ataxia telangiectasia and Rad3-related protein (ATR) kinase. The nucleoprotein complex protects the single-stranded DNA from nucleases, prevents formation of secondary structures that would interfere with repair, and co-ordinates the recruitment and departure of different genome maintenance factors. This subunit contains four oligonucleotide/oligosaccharide-binding (OB) domains, though the majority of ssDNA binding occurs in two of these domains. The heterotrimeric complex has two different modes of ssDNA binding, a low-affinity and high-affinity mode, determined by which ssDNA binding domains are utilized. The different binding modes differ in the length of DNA bound and in the proteins with which it interacts, thereby playing a role in regulating different genomic maintenance pathways. [provided by RefSeq, Sep 2017]
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human RPA1 expressed in E. Coli.
抗原种属
Human
基因名称
RPA1
基因ID
6117
蛋白名称
Replication protein A 70 kDa DNA-binding subunit
Uniprot ID
P27694
化学信息
分子量Theoretical: 68.1 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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  • 配液 计算器
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