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Anti-ROR1 Monoclonal Antibody (2M499) 是一种 Mouse 抗体,靶向 ROR1。Anti-ROR1 Monoclonal Antibody (2M499) 可用于 IF。
别名 NTRKR1, dJ537F10.1
Anti-ROR1 Monoclonal Antibody (2M499) 是一种 Mouse 抗体,靶向 ROR1。Anti-ROR1 Monoclonal Antibody (2M499) 可用于 IF。

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| 产品描述 | Anti-ROR1 Monoclonal Antibody (2M499) is a Mouse antibody targeting ROR1. Anti-ROR1 Monoclonal Antibody (2M499) can be used in IF. |
| 别名 | NTRKR1, dJ537F10.1 |
| Ig Type | IgG1 |
| 克隆号 | 2M499 |
| 反应种属 | Human |
| 应用 | IF |
| 推荐剂量 | IF: 1/200-1/1000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | PBS with 0.05% sodium azide. |
| 浓度 | 1 mg/mL |
| 研究背景 | ROR1, a type I membrane protein, is a receptor protein tyrosine kinase that modulates neurite growth in the central nervous system. The ROR-family receptor tyrosine kinases consist of two structurally related proteins, ROR1 and ROR2. These proteins are characterized by having intracellular tyrosine kinase domains, which are highly related to Trk-family kinases, extracellular Frizzled-like cysteine-rich domains (CRDs) and Kringle domains. The ROR family members are highly conserved among species, such as C. elegans, Drosophila, Xenopus and mammals. ROR1 and ROR2 are both involved in organogenesis with particular emphasis in neuronal differentiation. Increased expression of ROR1 in acute lymphoblastic leukemias (ALLs) as well as chronic lymphocytic leukemias (CLLs) implicate this protein as a potential tool for targeted immunotherapy in these diseases. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant extracellular fragment of human ROR1 (aa30-406) fused with hIgGFc tag, expressed in HEK293 cells |
| 抗原种属 | Human |
| 基因名称 | ROR1 |
| 基因ID | |
| 蛋白名称 | Inactive tyrosine-protein kinase transmembrane receptor ROR1 |
| Uniprot ID |
| 分子量 | Theoretical: 101 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |