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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-ROM-K/Kcnj1 Polyclonal Antibody

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货号 TMAB-12341

Anti-ROM-K/Kcnj1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ROM-K/Kcnj1。Anti-ROM-K/Kcnj1 Polyclonal Antibody 可用于 FCM。

Anti-ROM-K/Kcnj1 Polyclonal Antibody

Anti-ROM-K/Kcnj1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-12341

Anti-ROM-K/Kcnj1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ROM-K/Kcnj1。Anti-ROM-K/Kcnj1 Polyclonal Antibody 可用于 FCM。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-ROM-K/Kcnj1 Polyclonal Antibody is a Rabbit antibody targeting ROM-K/Kcnj1. Anti-ROM-K/Kcnj1 Polyclonal Antibody can be used in FCM.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Dog,Pig,Cow,Horse,Rabbit)
应用FCM
推荐剂量
FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Multi-pass membrane protein.
组织特异性In the kidney and pancreatic islets. Lower levels in skeletal muscle, pancreas, spleen, brain, heart and liver.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
抗原信息
免疫原
KLH conjugated synthetic peptide: human ROM-K/KCNJ1
抗原种属
Human
基因名称
KCNJ1
基因ID
3758
蛋白名称
ATP-sensitive inward rectifier potassium channel 1
Uniprot ID
P48048
功能
In the kidney, probably plays a major role in potassium homeostasis. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This channel is activated by internal ATP and can be blocked by external barium.
化学信息
分子量Theoretical: 45 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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