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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Robo4 Polyclonal Antibody

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货号 TMAB-12336

Anti-Robo4 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Robo4。Anti-Robo4 Polyclonal Antibody 可用于 WB。

Anti-Robo4 Polyclonal Antibody

Anti-Robo4 Polyclonal Antibody

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货号 TMAB-12336

Anti-Robo4 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Robo4。Anti-Robo4 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-Robo4 Polyclonal Antibody is a Rabbit antibody targeting Robo4. Anti-Robo4 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
组织特异性Specifically expressed in endothelial cells. Expressed at sites of angiogenesis in different tumor types.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Robo4 is a vascular specific receptor that is a repulsive cue to migrating endothelial cells during vascular development. Guidance and patterning of axons are orchestrated by cell surface receptors and ligands that provide directional cues. Interactions between the Robo receptor and Slit ligand families of proteins initiate signaling cascades that repel axonal outgrowth. In contrast to known neuronal Robo family members, the arrangement of the extracellular domains of Robo4 diverges significantly from that of all other Robo family members. Robo4 is specifically expressed in the vascular endothelium during murine embryonic development; the only Robo family member expressed in primary endothelial cells. Robo4 also has a role in regulating the migration of endothelial cells during tumor angiogenesis.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Robo4
抗原种属
Human
基因名称
ROBO4
基因ID
54538
蛋白名称
Roundabout homolog 4
功能
Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit protein.
化学信息
分子量Theoretical: 108 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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