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Anti-RNF3 Polyclonal Antibody

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货号 TMAB-12317

Anti-RNF3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 RNF3。Anti-RNF3 Polyclonal Antibody 可用于 WB。

Anti-RNF3 Polyclonal Antibody

Anti-RNF3 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-12317

Anti-RNF3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 RNF3。Anti-RNF3 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍


生物活性
产品描述
Anti-RNF3 Polyclonal Antibody is a Rabbit antibody targeting RNF3. Anti-RNF3 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Polycomb group (PcG) proteins form multiprotein complexes that regulate expression patterns of developmental and cell proliferation genes. Several members of the PcG contain ring finger domains and are identified as a subclass of RING finger proteins. The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain the RING-type zinc finger conserved domain are generally involved in the ubiquitination pathway of protein degradation. PCGF3 (polycomb group ring finger 3), also known as RNF3, DONG1 or RNF3A, is a 242 amino acid transcriptional regulator that is encoded by a gene located on human chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. PCGF3 exists as two isoforms produced by alternative splicing events.
抗原信息
免疫原
KLH conjugated synthetic peptide: human PCGF3/RNF3
抗原种属
Human
基因名称
PCGF3
基因ID
蛋白名称
Polycomb group RING finger protein 3
Uniprot ID
功能
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
化学信息
分子量Theoretical: 28 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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