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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-RNF149 Polyclonal Antibody

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货号 TMAB-12297

Anti-RNF149 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 RNF149。Anti-RNF149 Polyclonal Antibody 可用于 WB。

Anti-RNF149 Polyclonal Antibody

Anti-RNF149 Polyclonal Antibody

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货号 TMAB-12297

Anti-RNF149 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 RNF149。Anti-RNF149 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-RNF149 Polyclonal Antibody is a Rabbit antibody targeting RNF149. Anti-RNF149 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF149 (RING finger protein 149), also known as DNAPTP2 (DNA polymerase-transactivated protein 2) or E3 ubiquitin-protein ligase RNF149, is a 400 amino acid single-pass membrane protein that contains one PA (protease associated) domain and a single RING-type zinc finger. The gene encoding RNF149 maps to human chromosome 2, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alström syndrome.
抗原信息
免疫原
KLH conjugated synthetic peptide: human RNF149
抗原种属
Human
基因名称
RNF149
基因ID
284996
蛋白名称
E3 ubiquitin-protein ligase RNF149
Uniprot ID
Q8NC42
功能
E3 ubiquitin-protein ligase. Ubiquitinates BRAF, inducing its proteasomal degradation.
化学信息
分子量Theoretical: 40 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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