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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-RIN1 Polyclonal Antibody

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货号 TMAB-12258

Anti-RIN1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 RIN1。Anti-RIN1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-RIN1 Polyclonal Antibody

Anti-RIN1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-12258

Anti-RIN1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 RIN1。Anti-RIN1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-RIN1 Polyclonal Antibody is a Rabbit antibody targeting RIN1. Anti-RIN1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Pig,Cow)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Membrane. Cytoplasm, cytoskeleton. Note=Some amount is membrane-associated.
组织特异性Expressed in all tissues examined with high levels in brain, placenta and pancreas.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景RIN1 is a Ras effector protein which can affect Ras signaling in a variety of ways. It enhances signaling from ABL1 and ABL2 whcih are involved in regulation of cytoskeletal remodeling. It may function as a guanine nucleotide exchange factor in activation of Rab5a. Rin1 also competes with RAF1 for binding of the activated form of Ras. It may play a role inhibiting the modulation of neuronal plasticity in formation of aversive memory, and has been implicated as a tumor supressor gene in breast cancer.
抗原信息
免疫原
KLH conjugated synthetic peptide: human RIN1
抗原种属
Human
基因名称
RIN1
基因ID
9610
蛋白名称
Ras and Rab interactor 1
Uniprot ID
Q13671
功能
Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis.
化学信息
分子量Theoretical: 84 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

  • 稀释 计算器
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