购物车
您的购物车当前为空
Anti-RFA2 Monoclonal Antibody (1G867) 是一种 Mouse 抗体,靶向 RFA2。Anti-RFA2 Monoclonal Antibody (1G867) 可用于 WB,IHC,FCM。
别名 RP-A p34, RPA2, REPA2, RPA32, RPA34
Anti-RFA2 Monoclonal Antibody (1G867) 是一种 Mouse 抗体,靶向 RFA2。Anti-RFA2 Monoclonal Antibody (1G867) 可用于 WB,IHC,FCM。

TargetMol的所有产品仅用作科学研究或药证申报,不能被用于人体,我们不向个人提供产品和服务。请您遵守承诺用途,不得违反法律法规规定用于任何其他用途。
| 产品描述 | Anti-RFA2 Monoclonal Antibody (1G867) is a Mouse antibody targeting RFA2. Anti-RFA2 Monoclonal Antibody (1G867) can be used in WB,IHC,FCM. |
| 别名 | RP-A p34, RPA2, REPA2, RPA32, RPA34 |
| Ig Type | IgG1 |
| 克隆号 | 1G867 |
| 反应种属 | Human |
| 应用 | WBIHCFCM |
| 推荐剂量 | WB: 1/500-1/2000; IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | PBS with 0.05% sodium azide |
| 浓度 | 1 mg/mL |
| 研究背景 | This gene encodes a subunit of the heterotrimeric Replication Protein A (RPA) complex, which binds to single-stranded DNA (ssDNA), forming a nucleoprotein complex that plays an important role in DNA metabolism, being involved in DNA replication, repair, recombination, telomere maintenance, and co-ordinating the cellular response to DNA damage through activation of the ataxia telangiectasia and Rad3-related protein (ATR) kinase. The RPA complex protects single-stranded DNA from nucleases, prevents formation of secondary structures that would interfere with repair, and co-ordinates the recruitment and departure of different genome maintenance factors. The heterotrimeric complex has two different modes of ssDNA binding, a low-affinity and high-affinity mode, determined by which oligonucleotide/oligosaccharide-binding (OB) domains of the complex are utilized, and differing in the length of DNA bound. This subunit contains a single OB domain that participates in high-affinity DNA binding and also contains a winged helix domain at its carboxy terminus, which interacts with many genome maintenance protein. Post-translational modifications of the RPA complex also plays a role in co-ordinating different damage response pathways. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of human RFA2 expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | RPA2 |
| 基因ID | |
| 蛋白名称 | Replication protein A 32 kDa subunit |
| Uniprot ID |
| 分子量 | Theoretical: 29 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |