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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Reprimo Polyclonal Antibody

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货号 TMAB-12194

Anti-Reprimo Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Reprimo。Anti-Reprimo Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Reprimo Polyclonal Antibody

Anti-Reprimo Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-12194

Anti-Reprimo Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Reprimo。Anti-Reprimo Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-Reprimo Polyclonal Antibody is a Rabbit antibody targeting Reprimo. Anti-Reprimo Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Cow,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Membrane; Single-pass membrane protein (Potential).
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Reprimo, also known as TP53 dependent G2 arrest mediator candidate or RPRM, is a 109 amino acid cytoplasmic protein belonging to the Reprimo family, which is involved in the regulation of p53-dependent G2 arrest of the cell cycle. Reprimo may initiate cell cycle arrest by inhibiting CDC2 and nuclear translocation of the CDC2 cyclin B1 complex. A highly glycosylated protein, Reprimo also plays a role in cell cycle surveillance and DNA repair. Hypermethylation of Reprimo can lead to its transcriptional repression, which may increase pathogenesis of some types of human cancers. Reprimo has been identified as a potential biomarker for early detection multiple cancers. The gene encoding Reprimo maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Reprimo
抗原种属
Human
基因名称
RPRM
基因ID
56475
蛋白名称
Protein reprimo
功能
May be involved in the regulation of p53-dependent G2 arrest of the cell cycle. Seems to induce cell cycle arrest by inhibiting CDK1 activity and nuclear translocation of the CDC2 cyclin B1 comple.
化学信息
分子量Theoretical: 12 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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