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Anti-RENBP Polyclonal Antibody

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货号 TMAB-12188

Anti-RENBP Polyclonal Antibody 是一种 Rabbit 抗体,靶向 RENBP。Anti-RENBP Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-RENBP Polyclonal Antibody

Anti-RENBP Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-12188

Anti-RENBP Polyclonal Antibody 是一种 Rabbit 抗体,靶向 RENBP。Anti-RENBP Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍


生物活性
产品描述
Anti-RENBP Polyclonal Antibody is a Rabbit antibody targeting RENBP. Anti-RENBP Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Cow,Horse,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景RENBP is a 427 amino acid protein that is a proteinaceous renin inhibitor. In inhibiting renin, RENBP forms a complex with it; a high molecular weight renin. RENBP contains a leucine zipper domain, which is essential for its dimerization with renin. RENBP can catalyze the interconversion of N-acetylglucosamine to N-acetylmannosamine, indicating that it is a GlcNAc 2-epimerase. Sequences of porcine, human and rat renin-binding proteins are highly homologous. The RENBP gene is conserved in dog, mouse, rat and zebrafish, and maps to human chromosome Xq28 between DXS52 and G6PD. Rat Renbp is located on chromosome X at Xq37 close to marker DXWox3 and falls outside the BP QTL regions on chromosome X.
抗原信息
免疫原
KLH conjugated synthetic peptide: human RENBP
抗原种属
Human
基因名称
RENBP
基因ID
蛋白名称
N-acylglucosamine 2-epimerase
功能
Catalyzes the interconversion of N-acetylglucosamine to N-acetylmannosamine. Binds to renin forming a protein complex called high molecular weight (HMW) renin and inhibits rennin activity. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway: although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded.
化学信息
分子量Theoretical: 49 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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