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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Reelin Polyclonal Antibody

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货号 TMAB-12174

Anti-Reelin Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Reelin。Anti-Reelin Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Reelin Polyclonal Antibody

Anti-Reelin Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-12174

Anti-Reelin Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Reelin。Anti-Reelin Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-Reelin Polyclonal Antibody is a Rabbit antibody targeting Reelin. Anti-Reelin Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Chicken,Dog,Pig,Horse,GuineaPig)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted
组织特异性High level detected in plasma but also in extravascular fluids such as follicular and cerebrospinal fluids (at protein level).
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Reelin (or Reln) is a large glycoprotein that is secreted by Cajal-Retzius cells in the forebrain and by granule neurons in the cerebellum. Reelin was shown to be mutated in “reeler” mice, a mutation that is associated with widespread disruption of laminated regions of the brain, leading to impaired motor coordination, tremors and ataxia. Reelin protein expression is complex and changes throughout development. Reelin appears to function upstream of Dab1 in a signaling pathway that controls cell positioning in the developing brain and is also thought to be a direct effector of the neurotrophin BDNF.
抗原信息
免疫原
KLH conjugated synthetic peptide: human RELN
抗原种属
Human
基因名称
RELN
基因ID
5649
蛋白名称
Reelin
Uniprot ID
P78509
功能
This gene encodes a large secreted extracellular matrix protein thought to control cell-cell interactions critical for cell positioning and neuronal migration during brain development. This protein may be involved in schizophrenia, autism, bipolar disorder, major depression and in migration defects associated with temporal lobe epilepsy. Mutations of this gene are associated with autosomal recessive lissencephaly with cerebellar hypoplasia. Two transcript variants encoding distinct isoforms have been identified for this gene. Other transcript variants have been described but their full length nature has not been determined.
化学信息
分子量Theoretical: 400-450; 300; 180 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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