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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-RECK Polyclonal Antibody

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货号 TMAB-12172

Anti-RECK Polyclonal Antibody 是一种 Rabbit 抗体，靶向 RECK。Anti-RECK Polyclonal Antibody 可用于 WB,ELISA。

Anti-RECK Polyclonal Antibody

Anti-RECK Polyclonal Antibody

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货号 TMAB-12172

Anti-RECK Polyclonal Antibody 是一种 Rabbit 抗体，靶向 RECK。Anti-RECK Polyclonal Antibody 可用于 WB,ELISA。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-RECK Polyclonal Antibody is a Rabbit antibody targeting RECK. Anti-RECK Polyclonal Antibody can be used in WB,ELISA.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Dog,Pig,Cow,Rabbit,Sheep)
应用WBELISA
推荐剂量
WB: 1:500-2000; ELISA: 1:5000-10000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Lipid-anchor, GPI-anchor.
组织特异性Expressed in various tissues and untransformed cells. It is undetectable in tumor-derived cell lines and oncogenically transformed cells.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景RECK is a cysteine rich, extracellular protein with protease inhibitor like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. In normal cells, this membrane anchored glycoprotein may serve as a negative regulator for matrix metalloproteinase 9, a key enzyme involved in tumor invasion and metastasis.
抗原信息
免疫原
KLH conjugated synthetic peptide: human RECK
抗原种属
Human
基因名称
RECK
基因ID
313488
蛋白名称
Reversion-inducing cysteine-rich protein with Kazal motifs
Uniprot ID
O95980
功能
Negatively regulates matrix metalloproteinase-9 (MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK down-regulation by oncogenic signals may facilitate tumor invasion and metastasis. Appears to also regulate MMP-2 and MT1-MMP, which are involved in cancer progression.
化学信息
分子量Theoretical: 107 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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