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Anti-RBL2 Monoclonal Antibody (6H959) 是一种 Mouse 抗体,靶向 RBL2。Anti-RBL2 Monoclonal Antibody (6H959) 可用于 FCM。
别名 Rb2, P130
Anti-RBL2 Monoclonal Antibody (6H959) 是一种 Mouse 抗体,靶向 RBL2。Anti-RBL2 Monoclonal Antibody (6H959) 可用于 FCM。

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| 产品描述 | Anti-RBL2 Monoclonal Antibody (6H959) is a Mouse antibody targeting RBL2. Anti-RBL2 Monoclonal Antibody (6H959) can be used in FCM. |
| 别名 | Rb2, P130 |
| Ig Type | IgG1 |
| 克隆号 | 6H959 |
| 反应种属 | Human |
| 应用 | FCM |
| 推荐剂量 | FCM: 1/200-1/400 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | PBS with 0.05% sodium azide. |
| 浓度 | 1 mg/mL |
| 研究背景 | RBL2 is a Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV420H1 and SUV420H2, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation, associates preferentially with E2F5. Binds to cyclins A and E. Binds to and may be involved in the transforming capacity of the adenovirus E1A protein. May act as a tumor suppressor. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of human RBL2 (AA: 939-1139) expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | RBL2 |
| 基因ID | |
| 蛋白名称 | Retinoblastoma-like protein 2 |
| Uniprot ID |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |