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Anti-RB Monoclonal Antibody (5B616) 是一种 Mouse 抗体,靶向 RB。Anti-RB Monoclonal Antibody (5B616) 可用于 IHC。
别名 RB1, RB, pRb, pp110, p105-Rb, OSRC
Anti-RB Monoclonal Antibody (5B616) 是一种 Mouse 抗体,靶向 RB。Anti-RB Monoclonal Antibody (5B616) 可用于 IHC。

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| 产品描述 | Anti-RB Monoclonal Antibody (5B616) is a Mouse antibody targeting RB. Anti-RB Monoclonal Antibody (5B616) can be used in IHC. |
| 别名 | RB1, RB, pRb, pp110, p105-Rb, OSRC |
| Ig Type | IgG1 |
| 克隆号 | 5B616 |
| 反应种属 | Human |
| 应用 | IHC |
| 推荐剂量 | IHC: 1/200-1/1000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | Ascitic fluid containing 0.03% sodium azide |
| 浓度 | 1 mg/ml |
| 研究背景 | The Rb protein regulates differentiation, apoptosis, and cell cycle control by coordinating the cell cycle at G1-S with transcriptional machinery. During G1, cyclin D-dependent kinase-mediated phosphorylation of Rb at Ser-795 marks the conversion of Rb from a transcriptionally repressive, hypophosphorylated state to an inactive, phosphorylated state, which may be sustained through mitosis by differential phosphorylation of up to 16 putative serine or threonine residues. Pediatric cancer retinoblastoma and the formation of other human tumors can be attributed to mutations in the retinoblastoma tumor suppressor gene(Rb). |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of human RB expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | RB1 |
| 基因ID | |
| 蛋白名称 | Retinoblastoma-associated protein |
| Uniprot ID |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |