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Anti-RAF1 Monoclonal Antibody (4K700)

Synonyms: Raf-1, NS5, c-Raf, CRAF
货号 TMAT-0676 一键复制产品信息
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Anti-RAF1 Monoclonal Antibody (4K700) 是一种 Mouse 抗体,靶向 RAF1。Anti-RAF1 Monoclonal Antibody (4K700) 可用于 WB,IHC,FCM。

Anti-RAF1 Monoclonal Antibody (4K700)

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Rating icon 还可以
货号 TMAT-0676

别名 Raf-1, NS5, c-Raf, CRAF

Anti-RAF1 Monoclonal Antibody (4K700) 是一种 Mouse 抗体,靶向 RAF1。Anti-RAF1 Monoclonal Antibody (4K700) 可用于 WB,IHC,FCM。

Anti-RAF1 Monoclonal Antibody (4K700)
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产品介绍


生物活性
产品描述
Anti-RAF1 Monoclonal Antibody (4K700) is a Mouse antibody targeting RAF1. Anti-RAF1 Monoclonal Antibody (4K700) can be used in WB,IHC,FCM.
别名
Raf-1, NS5, c-Raf, CRAF
Ig Type
IgG1
克隆号
4K700
反应种属
Human
应用WBIHCFCM
推荐剂量
WB: 1/500-1/2000; IHC: 1/200-1/1000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/mL
研究背景This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human RAF1 expressed in E. Coli.
抗原种属
Human
基因名称
RAF1
基因ID
蛋白名称
RAF proto-oncogene serine/threonine-protein kinase
Uniprot ID
化学信息
分子量Theoretical: 73 kDa
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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