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Anti-RAF1 Monoclonal Antibody (4K700) 是一种 Mouse 抗体,靶向 RAF1。Anti-RAF1 Monoclonal Antibody (4K700) 可用于 WB,IHC,FCM。
别名 Raf-1, NS5, c-Raf, CRAF
Anti-RAF1 Monoclonal Antibody (4K700) 是一种 Mouse 抗体,靶向 RAF1。Anti-RAF1 Monoclonal Antibody (4K700) 可用于 WB,IHC,FCM。

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| 产品描述 | Anti-RAF1 Monoclonal Antibody (4K700) is a Mouse antibody targeting RAF1. Anti-RAF1 Monoclonal Antibody (4K700) can be used in WB,IHC,FCM. |
| 别名 | Raf-1, NS5, c-Raf, CRAF |
| Ig Type | IgG1 |
| 克隆号 | 4K700 |
| 反应种属 | Human |
| 应用 | WBIHCFCM |
| 推荐剂量 | WB: 1/500-1/2000; IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | PBS with 0.05% sodium azide |
| 浓度 | 1 mg/mL |
| 研究背景 | This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of human RAF1 expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | RAF1 |
| 基因ID | |
| 蛋白名称 | RAF proto-oncogene serine/threonine-protein kinase |
| Uniprot ID |
| 分子量 | Theoretical: 73 kDa |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |