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Anti-Pumilio 1 Polyclonal Antibody

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货号 TMAB-11945

Anti-Pumilio 1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Pumilio 1。Anti-Pumilio 1 Polyclonal Antibody 可用于 WB。

Anti-Pumilio 1 Polyclonal Antibody

Anti-Pumilio 1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-11945

Anti-Pumilio 1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Pumilio 1。Anti-Pumilio 1 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-Pumilio 1 Polyclonal Antibody is a Rabbit antibody targeting Pumilio 1. Anti-Pumilio 1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog,Pig,Cow,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm (Probable).
组织特异性Expressed in brain, heart, kidney, muscle, intestine and stomach. Not expressed in cerebellum, corpus callosum, caudate nucleus, hippocampus, medulla oblongata and putamen. Expressed in all fetal tissues tested.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Pumilio 1, also known as PUM1, PUMH1 (Pumilio homolog 1), HSPUM, PUMH or PUML1, is a homolog of the Drosophila Pumilio protein and belongs to the PUF family. The PUF family is comprised of evolutionarily conserved proteins that contain a C-terminal RNA binding domain made up of eight highly conserved tandem repeats. PUF proteins function as sequence-specific RNA-binding proteins and bind NREs (nanos response elements) in the 3’-untranslated regions of target mRNAs. They play an important role mediating mRNA stabilization and repressing translation. Pumilio 1 is a typical PUF protein expressed in fetal tissues as well as adult stomach, kidney, intestine, muscle, brain and heart tissues. Pumilio 1 localizes to the cytoplasm and is believed to participate in cell fate, cell development, cell differentiation and maintenance of somatic stem cells.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Pumilio 1
抗原种属
Human
基因名称
PUM1
基因ID
9698
蛋白名称
Pumilio homolog 1
Uniprot ID
Q14671
功能
Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. May be required to support proliferation and self-renewal of stem cells (By similarity).
化学信息
分子量Theoretical: 126 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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