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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-PTPRS Polyclonal Antibody

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货号 TMAB-11937

Anti-PTPRS Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PTPRS。Anti-PTPRS Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-PTPRS Polyclonal Antibody

Anti-PTPRS Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-11937

Anti-PTPRS Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PTPRS。Anti-PTPRS Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-PTPRS Polyclonal Antibody is a Rabbit antibody targeting PTPRS. Anti-PTPRS Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Single-pass type I membrane protein.
组织特异性Detected in all tissues tested except for placenta and liver.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
浓度1mg/ml
研究背景Protein tyrosine phosphatases, or PTPs, are type I transmembrane proteins, membrane associated proteins or proteins localized in nuclei. Examples of transmembrane PTPs are LAR, PTP alpha, PTP beta, PTP gamma, PTP delta, PTP epsilon, PTP zeta, PTP thet, PTP upsilon and PTPs. Transmembrane PTPsigma play diverse roles during development and in adult tissues. Immunodepletion studies have suggested LAR to be a regulator of insulin receptor phosphorylation. PTP alpha activity is increased twofold in response to phorbol ester stimulation, resulting in serine phosphorylation either directly or indirectly by members of the PKC family. Overexpression of v-H-Ras and Neu, but not Myc or Int2, in mammary tumors has been shown to induce PTPe expression. An alternative splicing event leads to a nervous tissue-specific chondroitin sulfate proteoglycan called phosphacan, which represents the amino terminal portion of PTP omega. PTP thet and PTP?share a conserved amino terminal 160 amino acid MAM domain which facilitates homophilic binding. PTP upsilon localizes to points of cell contact and may be involved in regulating the assembly and disassembly of cadherin/catenin complexes in vivo. PTPsigma contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. PTPsigma may also be involved in the molecular control of adult nerve repair. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported.
抗原信息
免疫原
KLH conjugated synthetic peptide: human PTPRS
抗原种属
Human
基因名称
PTPRS
基因ID
5802
蛋白名称
Receptor-type tyrosine-protein phosphatase S
Uniprot ID
Q13332
功能
Interacts with LAR-interacting protein LIP.1.
化学信息
分子量Theoretical: 214 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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