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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-PTPN12 Polyclonal Antibody

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货号 TMAB-11925

Anti-PTPN12 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PTPN12。Anti-PTPN12 Polyclonal Antibody 可用于 WB。

Anti-PTPN12 Polyclonal Antibody

Anti-PTPN12 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-11925

Anti-PTPN12 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PTPN12。Anti-PTPN12 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-PTPN12 Polyclonal Antibody is a Rabbit antibody targeting PTPN12. Anti-PTPN12 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. This PTP was also shown to interact with, and dephosphorylate, various products related to cytoskeletal structure and cell adhesion, such as p130 (Cas), CAKbeta/PTK2B, PSTPIP1, and paxillin. This suggests it has a regulatory role in controlling cell shape and mobility. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
抗原信息
免疫原
KLH conjugated synthetic peptide: human PTPN12
抗原种属
Human
基因名称
PTPN12
基因ID
5782
蛋白名称
Tyrosine-protein phosphatase non-receptor type 12
Uniprot ID
Q05209
功能
Dephosphorylates cellular tyrosine kinases, including PTK2B/PYK2, and thereby regulates signaling via PTK2B/PYK2.
化学信息
分子量Theoretical: 88 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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