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顶部产品介绍偶联与修饰抗原信息化学信息储存和溶解信息计算器

Anti-PTPN1 Monoclonal Antibody (5I181)

Synonyms: PTP1B
货号 TMAT-0879 一键复制产品信息
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Anti-PTPN1 Monoclonal Antibody (5I181) 是一种 Mouse 抗体，靶向 PTPN1。Anti-PTPN1 Monoclonal Antibody (5I181) 可用于 WB,IHC,IF,FCM。

Anti-PTPN1 Monoclonal Antibody (5I181)

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Rating icon 还可以
货号 TMAT-0879

别名 PTP1B

Anti-PTPN1 Monoclonal Antibody (5I181) 是一种 Mouse 抗体，靶向 PTPN1。Anti-PTPN1 Monoclonal Antibody (5I181) 可用于 WB,IHC,IF,FCM。

Anti-PTPN1 Monoclonal Antibody (5I181)
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产品介绍

生物活性
产品描述
Anti-PTPN1 Monoclonal Antibody (5I181) is a Mouse antibody targeting PTPN1. Anti-PTPN1 Monoclonal Antibody (5I181) can be used in WB,IHC,IF,FCM.
别名
PTP1B
Ig Type
IgG1
克隆号
5I181
反应种属
Human
应用WBIHCIFFCM
推荐剂量
WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide.
浓度1 mg/mL
研究背景The protein encoded by this gene is the founding member of the protein tyrosine phosphatase (PTP) family, which was isolated and identified based on its enzymatic activity and amino acid sequence. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP has been shown to act as a negative regulator of insulin signaling by dephosphorylating the phosphotryosine residues of insulin receptor kinase. This PTP was also reported to dephosphorylate epidermal growth factor receptor kinase, as well as JAK2 and TYK2 kinases, which implicated the role of this PTP in cell growth control, and cell response to interferon stimulation. Two transcript variants encoding different isoforms have been found for this gene.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human PTPN1 (AA: 40-246) expressed in E. Coli.
抗原种属
Human
基因名称
PTPN1
基因ID
5770
蛋白名称
Tyrosine-protein phosphatase non-receptor type 1
Uniprot ID
P18031
化学信息
分子量Theoretical: 50 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器
  • 配液 计算器
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