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Anti-PTPH1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 PTPH1。Anti-PTPH1 Polyclonal Antibody 可用于 WB。
Anti-PTPH1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 PTPH1。Anti-PTPH1 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
| 产品描述 | Anti-PTPH1 Polyclonal Antibody is a Rabbit antibody targeting PTPH1. Anti-PTPH1 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Human (predicted:Mouse,Rat,Dog,Cow,Horse,Sheep) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cell membrane. Cytoplasm. cytoskeleton. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | The phosphorylation of proteins at tyrosine residues has long been recognized as an important regulatory component of signal transduction. This is a reversible process, involving both enzymes that phosphorylate proteins on tyrosine residues as well as a rapidly expanding family of protein tyrosine phosphatases. These latter enzymes bear little resemblance to either the protein serine and protein threonine phosphatases or to the acid and alkaline phosphatases. In most tissues, the major PTPase is a vanadate- and molybdate-sensitive protein. PTP-H1 shares homology with the cytoskeletal-associated proteins band 4.1, ezrin, and talin and has been shown to contain a PDZ and band 4.1 domain. These domains are responsible for targeting proteins to the cytoskeleton-membrane interface, as well as mediating protein-protein interactions, recognizing C-terminal valine residues and binding to other PDZ domains. Overexpression of PTP-H1 may reverse transformation induced by oncogenic protein-tyrosine kinases, such as the members of the src family. |
| 免疫原 | KLH conjugated synthetic peptide: human PTPH1/PTPN3 |
| 抗原种属 | Human |
| 基因名称 | PTPN3 |
| 基因ID | |
| 蛋白名称 | Tyrosine-protein phosphatase non-receptor type 3 |
| Uniprot ID | |
| 功能 | May act at junctions between the membrane and the cytoskeleton. Possesses tyrosine phosphatase activity. |
| 分子量 | Theoretical: 104 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |