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Anti-PTPH1 Polyclonal Antibody

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货号 TMAB-11916

Anti-PTPH1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 PTPH1。Anti-PTPH1 Polyclonal Antibody 可用于 WB。

Anti-PTPH1 Polyclonal Antibody

Anti-PTPH1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-11916

Anti-PTPH1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 PTPH1。Anti-PTPH1 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-PTPH1 Polyclonal Antibody is a Rabbit antibody targeting PTPH1. Anti-PTPH1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Cow,Horse,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane. Cytoplasm. cytoskeleton.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The phosphorylation of proteins at tyrosine residues has long been recognized as an important regulatory component of signal transduction. This is a reversible process, involving both enzymes that phosphorylate proteins on tyrosine residues as well as a rapidly expanding family of protein tyrosine phosphatases. These latter enzymes bear little resemblance to either the protein serine and protein threonine phosphatases or to the acid and alkaline phosphatases. In most tissues, the major PTPase is a vanadate- and molybdate-sensitive protein. PTP-H1 shares homology with the cytoskeletal-associated proteins band 4.1, ezrin, and talin and has been shown to contain a PDZ and band 4.1 domain. These domains are responsible for targeting proteins to the cytoskeleton-membrane interface, as well as mediating protein-protein interactions, recognizing C-terminal valine residues and binding to other PDZ domains. Overexpression of PTP-H1 may reverse transformation induced by oncogenic protein-tyrosine kinases, such as the members of the src family.
抗原信息
免疫原
KLH conjugated synthetic peptide: human PTPH1/PTPN3
抗原种属
Human
基因名称
PTPN3
基因ID
蛋白名称
Tyrosine-protein phosphatase non-receptor type 3
Uniprot ID
功能
May act at junctions between the membrane and the cytoskeleton. Possesses tyrosine phosphatase activity.
化学信息
分子量Theoretical: 104 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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