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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Prune homolog 2/C9orf65 Polyclonal Antibody

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货号 TMAB-11841

Anti-Prune homolog 2/C9orf65 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Prune homolog 2/C9orf65。Anti-Prune homolog 2/C9orf65 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-Prune homolog 2/C9orf65 Polyclonal Antibody

Anti-Prune homolog 2/C9orf65 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-11841

Anti-Prune homolog 2/C9orf65 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Prune homolog 2/C9orf65。Anti-Prune homolog 2/C9orf65 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-Prune homolog 2/C9orf65 Polyclonal Antibody is a Rabbit antibody targeting Prune homolog 2/C9orf65. Anti-Prune homolog 2/C9orf65 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus. Cell junction ?focal adhesion
组织特异性Ubiquitously expressed. Seems to be overexpressed in aggressive sarcoma subtypes, such as leiomyosarcomas and malignant fibrous histiocytomas (MFH) as well as in the less malignant liposarcomas.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene belongs to the B-cell CLL/lymphoma 2 and adenovirus E1B 19 kDa interacting family, whose members play roles in many cellular processes including apotosis, cell transformation, and synaptic function. Several functions for this protein have been demonstrated including suppression of Ras homolog family member A activity, which results in reduced stress fiber formation and suppression of oncogenic cellular transformation. A high molecular weight isoform of this protein has also been shown to colocalize with Adaptor protein complex 2, beta-Adaptin and endodermal markers, suggesting an involvement in post-endocytic trafficking. In prostate cancer cells, this gene acts as a tumor suppressor and its expression is regulated by prostate cancer antigen 3, a non-protein coding gene on the opposite DNA strand in an intron of this gene. Prostate cancer antigen 3 regulates levels of this gene through formation of a double-stranded RNA that undergoes adenosine deaminase actin on RNA-dependent adenosine-to-inosine RNA editing. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
抗原信息
免疫原
KLH conjugated synthetic peptide: human Prune homolog 2/C9orf56
抗原种属
Human
基因名称
PRUNE2
基因ID
158471
蛋白名称
Protein prune homolog 2
Uniprot ID
Q8WUY3
功能
Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. Plays a role in cell proliferation, is able to induce cell motility and acts as a negative regulator of NME1.
化学信息
分子量Theoretical: 341 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

  • 稀释 计算器
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