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Anti-Profilin 1 Polyclonal Antibody

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货号 TMAB-11768

Anti-Profilin 1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Profilin 1。Anti-Profilin 1 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF,FCM。

Anti-Profilin 1 Polyclonal Antibody

Anti-Profilin 1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-11768

Anti-Profilin 1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Profilin 1。Anti-Profilin 1 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF,FCM。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

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产品描述
Anti-Profilin 1 Polyclonal Antibody is a Rabbit antibody targeting Profilin 1. Anti-Profilin 1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Dog,Cow,Horse)
应用WBIHC-PIHC-FrIFFCM
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 3μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm, cytoskeleton.
组织特异性Expressed in epididymis (at protein level).
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Profilin 1 is a ubiquitous actin monomer-binding protein involved in actin polymerization in response to extracellular signals. Three profilin genes have been identified: profilin 1, 2, and 3. Profilin 1 is the most ubiquitous and abundant, and is highly expressed throughout development and adulthood inmost tissues including brain. Profilin 2 is the neuronal specific isoform and profilin 3 is a testis specific isoform. Profilins of eukaryotic cells are small (12-15 kDa) cytoplasmic proteins that bind to actin monomers, polyphosphoinositides and polymers of L-proline. Profilins were shown to be important for normal cell proliferation, differentiation and motility. Deletion of profilin 1 gene leads to an embryonic lethal phenotype.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Profilin 1
抗原种属
Human
基因名称
PFN1
基因ID
5216
蛋白名称
Profilin-1
Uniprot ID
P07737
功能
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR.
化学信息
分子量Theoretical: 15 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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