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Anti-Pregnancy zone protein Polyclonal Antibody

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货号 TMAB-11723

Anti-Pregnancy zone protein Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Pregnancy zone protein。Anti-Pregnancy zone protein Polyclonal Antibody 可用于 WB。

Anti-Pregnancy zone protein Polyclonal Antibody

Anti-Pregnancy zone protein Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-11723

Anti-Pregnancy zone protein Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Pregnancy zone protein。Anti-Pregnancy zone protein Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-Pregnancy zone protein Polyclonal Antibody is a Rabbit antibody targeting Pregnancy zone protein. Anti-Pregnancy zone protein Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog,Cow,Horse,Rabbit)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Pregnancy Zone protein is a 1,482 amino acid secreted protein that belongs to the protease inhibitor I39 family and exists as multiple alternatively spliced isoforms. Expressed predominately in plasma and in late-pregnancy sera, Pregnancy Zone protein functions as a disulfide-linked homotetramer that is able to trap and inhibit proteinases, thus playing a role in the regulation of protein splitting and small peptide formation. The gene encoding Pregnancy Zone protein maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and Trisomy 12p, which causes facial developmental defects and seizure disorders.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Pregnancy zone protein
抗原种属
Human
基因名称
PZP
基因ID
5858
蛋白名称
Pregnancy zone protein
Uniprot ID
P20742
功能
Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.
化学信息
分子量Theoretical: 161 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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