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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-PP2CA Polyclonal Antibody

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货号 TMAB-11648

Anti-PP2CA Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PP2CA。Anti-PP2CA Polyclonal Antibody 可用于 IHC-P,IHC-Fr,ICC/IF,IF,FCM。

Anti-PP2CA Polyclonal Antibody

Anti-PP2CA Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-11648

Anti-PP2CA Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PP2CA。Anti-PP2CA Polyclonal Antibody 可用于 IHC-P,IHC-Fr,ICC/IF,IF,FCM。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-PP2CA Polyclonal Antibody is a Rabbit antibody targeting PP2CA. Anti-PP2CA Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF,FCM.
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse,Chicken,Dog,Cow,Horse,Rabbit,Sheep)
应用IHC-PIHC-FrICC/IFIFFCM
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; FCM: 3μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase dephosphorylates, and negatively regulates the activities of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the activation of p38 and JNK kinase cascades induced by environmental stresses. This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to activate the expression of the tumor suppressor gene TP53/p53, which leads to G2/M cell cycle arrest and apoptosis. Three alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].
抗原信息
免疫原
KLH conjugated synthetic peptide: human PP2CA/PPM1A
抗原种属
Human
基因名称
PPM1A
基因ID
5494
蛋白名称
Protein phosphatase 1A
Uniprot ID
P35813
功能
Enzyme with a broad specificity. Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling.
化学信息
分子量Theoretical: 42 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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