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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-POLK Polyclonal Antibody 2

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货号 TMAB-11623

Anti-POLK Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 POLK。Anti-POLK Polyclonal Antibody 2 可用于 FCM。

Anti-POLK Polyclonal Antibody 2

Anti-POLK Polyclonal Antibody 2

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Rating icon 还可以
货号 TMAB-11623

Anti-POLK Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 POLK。Anti-POLK Polyclonal Antibody 2 可用于 FCM。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-POLK Polyclonal Antibody 2 is a Rabbit antibody targeting POLK. Anti-POLK Polyclonal Antibody 2 can be used in FCM.
Ig Type
IgG
反应种属
Human
应用FCM
推荐剂量
FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Accumulates at replication forks after DNA damage.
组织特异性Detected at low levels in testis, spleen, prostate and ovary. Detected at very low levels in kidney, colon, brain, heart, liver, lung, placenta, pancreas and peripheral blood leukocytes.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a member of the DNA polymerase type-Y family of proteins. The encoded protein is a specialized DNA polymerase that catalyzes translesion DNA synthesis, which allows DNA replication in the presence of DNA lesions. Human cell lines lacking a functional copy of this gene exhibit impaired genome integrity and enhanced susceptibility to oxidative damage. Mutations in this gene that impair enzyme activity may be associated with prostate cancer in human patients. [provided by RefSeq, Sep 2016]
抗原信息
免疫原
KLH conjugated synthetic peptide: human POLK
抗原种属
Human
基因名称
POLK
基因ID
51426
蛋白名称
DNA polymerase kappa
功能
Error-prone DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Favors Hoogsteen base-pairing in the active site. Inserts the correct base with high-fidelity opposite an adenosine template. Exhibits low fidelity and efficiency opposite a thymidine template, where it will preferentially insert guanosine. May play a role in hypermutation of immunogobulin genes. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but may not have lyase activity.
化学信息
分子量Theoretical: 99 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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