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Anti-POLG Polyclonal Antibody

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货号 TMAB-11621

Anti-POLG Polyclonal Antibody 是一种 Rabbit 抗体,靶向 POLG。Anti-POLG Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-POLG Polyclonal Antibody

Anti-POLG Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-11621

Anti-POLG Polyclonal Antibody 是一种 Rabbit 抗体,靶向 POLG。Anti-POLG Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍


生物活性
产品描述
Anti-POLG Polyclonal Antibody is a Rabbit antibody targeting POLG. Anti-POLG Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Pig)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Mitochondrion.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景DNA replication, recombination and repair, all of which are necessary for genomic stability, require the presence of exonucleases. In DNA replication, these enzymes are involved in the processing of Okazaki fragments, whereas in DNA repair, they function to excise damaged DNA fragments and correct recombinational mismatches. These exonucleases include the family of DNA polymerases (DNA pol). DNA pol Alpha, Beta, Gamma, and epsilon are involved in DNA replication and repair. DNA pol gamma and DNA pol e are multi-subunit enzymes, with DNA pol gamma consisting of two subunits: p125, which interacts with the sliding DNA clamp protein, PCNA, and p50. The nuclear-encoded DNA pol Delta is the only DNA polymerase required for the replication of the mitochondrial DNA. DNA pol zeta is ubiquitously expressed in various tissues and mediates the cellular mechanism of damage-induced mutagenesis. DNA pol theta is a DNA polymerase-helicase that binds ATP and is involved in the repair of interstrand crosslinks.
抗原信息
免疫原
KLH conjugated synthetic peptide: human POLG
抗原种属
Human
基因名称
POLG
基因ID
蛋白名称
DNA polymerase subunit gamma-1
Uniprot ID
功能
Involved in the replication of mitochondrial DNA.
化学信息
分子量Theoretical: 140 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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