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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-PMS2 Monoclonal Antibody (7W250)

Synonyms: PMSL2, PMS2CL, MLH4, HNPCC4
货号 TMAT-1119 一键复制产品信息
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Anti-PMS2 Monoclonal Antibody (7W250) 是一种 Mouse 抗体，靶向 PMS2。Anti-PMS2 Monoclonal Antibody (7W250) 可用于 IHC,FCM。

Anti-PMS2 Monoclonal Antibody (7W250)

一键复制产品信息
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货号 TMAT-1119

别名 PMSL2, PMS2CL, MLH4, HNPCC4

Anti-PMS2 Monoclonal Antibody (7W250) 是一种 Mouse 抗体，靶向 PMS2。Anti-PMS2 Monoclonal Antibody (7W250) 可用于 IHC,FCM。

Anti-PMS2 Monoclonal Antibody (7W250)
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产品介绍

生物活性
产品描述
Anti-PMS2 Monoclonal Antibody (7W250) is a Mouse antibody targeting PMS2. Anti-PMS2 Monoclonal Antibody (7W250) can be used in IHC,FCM.
别名
PMSL2, PMS2CL, MLH4, HNPCC4
Ig Type
IgG1
克隆号
7W250
反应种属
Human
应用IHCFCM
推荐剂量
IHC: 1/200-1/1000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/mL
研究背景The protein encoded by this gene is a key component of the mismatch repair system that functions to correct DNA mismatches and small insertions and deletions that can occur during DNA replication and homologous recombination. This protein forms heterodimers with the gene product of the mutL homolog 1 (MLH1) gene to form the MutL-alpha heterodimer. The MutL-alpha heterodimer possesses an endonucleolytic activity that is activated following recognition of mismatches and insertion/deletion loops by the MutS-alpha and MutS-beta heterodimers, and is necessary for removal of the mismatched DNA. There is a DQHA(X)2E(X)4E motif found at the C-terminus of the protein encoded by this gene that forms part of the active site of the nuclease. Mutations in this gene have been associated with hereditary nonpolyposis colorectal cancer (HNPCC; also known as Lynch syndrome) and Turcot syndrome.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human PMS2 (AA: (431-580)) expressed in E. Coli.
抗原种属
Human
基因名称
PMS2
基因ID
5395
蛋白名称
Mismatch repair endonuclease PMS2
Uniprot ID
P54278
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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