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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-PLEKHA7 Polyclonal Antibody

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货号 TMAB-11544

Anti-PLEKHA7 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PLEKHA7。Anti-PLEKHA7 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-PLEKHA7 Polyclonal Antibody

Anti-PLEKHA7 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-11544

Anti-PLEKHA7 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PLEKHA7。Anti-PLEKHA7 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-PLEKHA7 Polyclonal Antibody is a Rabbit antibody targeting PLEKHA7. Anti-PLEKHA7 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell junction > adherens junction. Cytoplasm. Cytoplasm > cytoskeleton > centrosome. Localizes to zonula adherens, recruited via its interaction with CTNND1.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景PLEKHA7 (pleckstrin homology domain containing, family A member 7), also known as PH domain-containing family A member 7, is a 1,121 amino acid protein that contains one PH domain and two WW domains. Encoded by a gene that maps to human chromosome 11p15.1, PLEKHA7 exists as three alternatively spliced isoforms. Localizing to cell-cell junctions in Caco2 cells, PLEKHA7 interacts with the adherens junction protein p120 in human colon carcinoma cells. PLEKHA7 also colocalizes with zona adherens proteins and is necessary for zonula adherens biogenesis and maintenance. Associated with systolic blood pressure (SBP) and hypertension, PLEKHA7 is a potential target for the prevention or treatment of hypertension. PLEKHA7 is also linked to autoimmune hepatitis type 1, a chronic active hepatitis characterized by hypergammaglobulinemia and autoantibodies.
抗原信息
免疫原
KLH conjugated synthetic peptide: human PLEKHA7
抗原种属
Human
基因名称
PLEKHA7
基因ID
144100
蛋白名称
Pleckstrin homology domain-containing family A member 7
Uniprot ID
Q6IQ23
功能
Required for zonula adherens biogenesis and maintenance. Acts via its interaction with KIAA1543/Nezha, which anchors microtubules at their minus-ends to zonula adherens, leading to recruit KIFC3 kinesin to junctional site.
化学信息
分子量Theoretical: 127 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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