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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-plasma kallikrein B1 heavy chain Polyclonal Antibody

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货号 TMAB-11523

Anti-plasma kallikrein B1 heavy chain Polyclonal Antibody 是一种 Rabbit 抗体，靶向 plasma kallikrein B1 heavy chain。Anti-plasma kallikrein B1 heavy chain Polyclonal Antibody 可用于 WB。

Anti-plasma kallikrein B1 heavy chain Polyclonal Antibody

Anti-plasma kallikrein B1 heavy chain Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-11523

Anti-plasma kallikrein B1 heavy chain Polyclonal Antibody 是一种 Rabbit 抗体，靶向 plasma kallikrein B1 heavy chain。Anti-plasma kallikrein B1 heavy chain Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-plasma kallikrein B1 heavy chain Polyclonal Antibody is a Rabbit antibody targeting plasma kallikrein B1 heavy chain. Anti-plasma kallikrein B1 heavy chain Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Cow)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Plasma prekallikrein is a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. It is synthesized in the liver and secreted into the blood as a single polypeptide chain. Plasma prekallikrein is converted to plasma kallikrein by factor XIIa by the cleavage of an internal Arg-Ile bond. Plasma kallikrein therefore is composed of a heavy chain and a light chain held together by a disulphide bond. The heavy chain originates from the amino-terminal end of the zymogen and contains 4 tandem repeats of 90 or 91 amino acids. Each repeat harbors a novel structure called the apple domain. The heavy chain is required for the surface-dependent pro-coagulant activity of plasma kallikrein. The light chain contains the active site or catalytic domain of the enzyme and is homologous to the trypsin family of serine proteases. Plasma prekallikrein deficiency causes a prolonged activated partial thromboplastin time in patients. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
KLH conjugated synthetic peptide: human plasma kallikrein B1 heavy chain
抗原种属
Human
基因名称
KLKB1
基因ID
3818
蛋白名称
Plasma kallikrein
Uniprot ID
P03952
功能
The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin.
化学信息
分子量Theoretical: 41 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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