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Anti-Plakophilin 2 Polyclonal Antibody

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货号 TMAB-11521

Anti-Plakophilin 2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Plakophilin 2。Anti-Plakophilin 2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Plakophilin 2 Polyclonal Antibody

Anti-Plakophilin 2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-11521

Anti-Plakophilin 2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Plakophilin 2。Anti-Plakophilin 2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
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100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-Plakophilin 2 Polyclonal Antibody is a Rabbit antibody targeting Plakophilin 2. Anti-Plakophilin 2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cell junction, desmosome.Note=Nuclear and associated with desmosomes.
组织特异性Widely expressed. Found at desmosomal plaques in simple and stratified epithelia and in non-epithelial tissues such as myocardium and lymph node follicles. In most stratified epithelia found in the desmosomes of the basal cell layer and seems to be absent from suprabasal strata.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Plakophilins 1, 2, 3 and 4 (PKP1-4) influence development and participate in linking cadherins to cytoskeletal intermediate filaments. Plakophilins 1-4 contain arm-repeat (armadillo) domains, and localize to nuclei and cell desmosomes (cell-cell junctions found in suprabasal layers of stratifying epithelia that undergo mechanical stress). Plakophilin-1 mediates increases in desmosomal protein content, desmosome assembly, and regulation of cell migration. Plakophilin-2 is important for desmosome assembly and is an essential morphogenic factor and architectural component of the heart. Plakophilin-3 plays a role in both desmosome-dependent adhesion and signaling pathways. Plakophilin-4 is a component of desmosomal adhesion plaques that regulates junctional plaque organization and cadherin function.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Plakophilin 2
抗原种属
Human
基因名称
PKP2
基因ID
5318
蛋白名称
Plakophilin-2
Uniprot ID
Q99959
功能
May play a role in junctional plaques.
化学信息
分子量Theoretical: 97 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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